FluMist vaccine
Thanks Char, for this excellent post. First it was the direct assault on the blood (see: The Sanctity Of Human Blood: Vaccination I$ Not Immunization) now it's the brain. Breaking natural safeguards to our vitally protected blood and brain is a no no. Why do you think nature went through all the hoops and loops to protect them from external contamination in the first place? Please be aware that there will be consequences for violating these protections and I don't mean profits for the medical Mafia!
Chris Gupta
What is potentially bothersome is the fact that the nerves in the nose are a direct pathway to the brain, and bypass the blood-brain barrier. See Fields Virology which states "the olfactory tract has long been recognized as (a) an alternative pathway to the CNS, and (b) an important mode of spread after aerosol exposure." In the case of flaviviruses (which are admittedly not the same as influenza viruses), the text continues: "Intranasal inoculation of flaviviruses may result in lethal encephalitis, presumably by direct infection of olfactory neurons and spread through the olfactory tract to the brain, whereas peripheral inoculation of the same virus strains does not result in neuroinvasion. However, olfactory neurons may also provide a route for CNS infection after peripheral virus infection." (2)
The point being, one might want to be very cautious regarding allowing things to be sprayed up one's nose.Please be advised that the new FluMist nasal vaccine states in its package insert, that there is monosodium glutamate (MSG) used in the buffer that stabilizes the allantoic fluid harvested from the chicken eggs containing the live influenza virus. Specifically, "the allantoic fluid of these eggs is harvested, clarified by centrifugation, and stabilized with buffer containing sucrose, potassium phosphate, and monosodium glutamate (0.47 mg/dose)." (1)
What is potentially bothersome is the fact that the nerves in the nose are a direct pathway to the brain, and bypass the blood-brain barrier. See Fields Virology which states "the olfactory tract has long been recognized as (a) an alternative pathway to the CNS, and (b) an important mode of spread after aerosol exposure." In the case of flaviviruses (which are admittedly not the same as influenza viruses), the text continues: "Intranasal inoculation of flaviviruses may result in lethal encephalitis, presumably by direct infection of olfactory neurons and spread through the olfactory tract to the brain, whereas peripheral inoculation of the same virus strains does not result in neuroinvasion. However, olfactory neurons may also provide a route for CNS infection after peripheral virus infection." (2)
The point being, one might want to be very cautious regarding allowing things to be sprayed up one's nose.
The package insert states that there are no preservatives in the vaccine per se, and that the virus is cultured on pathogen-free eggs. However, as previously discussed on these lists, the chicken genome itself may contain hidden retroviruses; and there is known to be significant amounts of animal DNA that is left in vaccines during the manufacturing process, not to mention other contamination possibilities. So, common sense might indicate that, for these reasons it might not be in one's best (healthful) interest to put these materials into one's nose. An ordinary flu shot might be a safer route (if necessary). Of course, this is not intended to constitute medical advice, but is meant to inform the reader of additional information in the public domain.
References
1. The package insert can be reviewed at: http://www.medimmune.com then click on "more information" in the FluMist box; click directly on "prescribing information here" for a PDF copy of the package insert.
2. Knipe, David M, ed. Fields Virology. Philadelphia: Lippincott, 4th ed. 2001. P. 1057.
Best wishes,
Char
posted by Chris Gupta on Wednesday August 27 2003
updated on Saturday September 24 2005URL of this article:
http://www.newmediaexplorer.org/chris/2003/08/27/flumist_vaccine.htm
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