Drano' for arteries works in 6 weeks
Thanks Susan, for the post. I am afraid this sort of thing does not impress me at all, as most of these news release teasers are just there to give us the illusion of progress and serve to mostly to drum up, never ending, funding. Note the comment "...but he said that commercial use is probably a few years off." meanwhile give us more funds...
There is good reason why plaque exists - it's natures way of reinforcing weakened arterial walls due to nutritional deficiencies (like nearly all diseases), primarily vitamins C and B6 see:
Sadly the easy cost effective nutritional approach is and will continue to be po pooed in lieu of the high funding potential of smoke and mirrors solutions.
see: Orthomolecular Solutions to Heart Disease
Chris Gupta
At 10:57 PM 11/9/2003 -0500, Susan Koswan wrote:
Hi Chris,
There was an article in this week's Record about intravenously injecting "good" cholesterol and it worked like Drano to clear clogged arteries in 6 weeks. See below. What do you think?
Susan Koswan
'Drano' for arteries works in 6 weeks
GOOD' CHOLESTEROL CAN CLEAR PLAQUE
(Nov 6, 2003)
Intravenous doses of a synthetic component of "good'' cholesterol reduced artery disease in just six weeks in a small study with startlingly big implications for treating North America's No. 1 killer.
"The concept is sort of liquid Drano for the coronary arteries,'' said Dr. Steven Nissen, a Cleveland Clinic cardiologist who led the study.
Larger and longer studies need to be done to determine if the experimental treatment will translate into fewer deaths, but the early results are promising, said Dr. Daniel Rader, director of preventive cardiology at the University of Pennsylvania School of Medicine.
The treatment used a laboratory-produced version of an unusually effective form of HDL, the good cholesterol that helps protect against heart disease by removing plaque, or fatty buildups, from the bloodstream.
"This is clearly on the level of a breakthrough that will have far-reaching implications,'' pointing the way toward a rapid treatment for fatty buildups, said Dr. Bryan Brewer, chief of molecular diseases at the U.S. National Heart, Lung and Blood Institute.
The surprisingly quick results, though preliminary, shatter a long-standing belief that heart disease is a slow-progressing disease that takes a long time to undo, said Rader, who wrote an editorial accompanying the study in yesterday's Journal of the American Medical Association.
While some existing medicines target HDL, most conventional drug treatment works by reducing levels of LDL cholesterol, the bad kind that contributes to the formation of plaques that can clog arteries and lead to heart attacks.
Nissen's study is part of a burgeoning area of research that focuses on treatments that raise HDL levels or improve HDL's plaque-fighting abilities.
His findings stem from an unusual discovery about 25 years ago in the northern Italian village of Limone Sul Gardia. Italian researchers found that 40 residents there had very low HDL levels, yet paradoxically had low rates of coronary artery disease.
Lab tests revealed a likely explanation: All had a gene variation in a key protein component of HDL.
The variation contributed to larger-than-normal HDL particles, which is believed to make HDL cholesterol especially efficient at removing plaque.
Scientists made a synthetic form of the protein, which was found to reduce plaque buildups rapidly in mice and rabbits.
The study was funded by Esperion Therapeutics Inc. of Ann Arbor, Mich., a biotechnology company that makes the product.
In the study, 36 patients who had had heart attacks or severe chest pain received weekly intravenous infusions of the substance for five weeks. Eleven patients received dummy treatments.
At six weeks, imaging tests showed the patients receiving the synthetic protein had a visible four per cent reduction in plaque buildup in coronary arteries. There was no significant change in the placebo group.
Nissen envisions the treatment being used in combination with other therapy including LDL-lowering drugs, but he said that commercial use is probably a few years off.
GOOD' CHOLESTEROL CAN CLEAR PLAQUE
Infusions of a synthetic ocmponent of 'good' cholesterol or HDL, reduced artery disease in just five weeks in a small study that could have bigger implications for treating the nation's leading killer.
Diesase in the arteries
Excess deposits of cholesterol can build up in artery walls causing plaque and reducing blood flow. Pieces of plaque can break off and clog veins.
Infusing the blood
HDL that has a component that contributes to larger-than-normal sized particles is infused into the blood. It is especially effective at removing plaque.
Cleaning the arteries
HDL enters the arterial wall and pulls cholesterol from the lining.
Eliminating plaque
Excess cholesterol is removed and transported back to the liver for elimination.
SOURCES: Journal of the American Medical Association; Esperion Theraputics, Inc.
N. Rapp, C. New/AP
----- Original Message -----
From: Chris Gupta
To: Recipient list suppressed
Sent: Sunday, November 09, 2003 10:18 PM
Subject: Low-Fat, High-Carb Diet for Morbidly Obese Tied to Liver InflammationOnce again doctors are doing opposite of what's best for the patient - good for business, though.
Zoe Lenska
**********
posted by Chris Gupta on Wednesday November 12 2003
updated on Saturday September 24 2005URL of this article:
http://www.newmediaexplorer.org/chris/2003/11/12/drano_for_arteries_works_in_6_weeks.htm
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