Lipitor - The Human Cost

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Health

Pharma

Lipitor, a cholesterol lowering drug made by Pfizer and sold to millions of health conscious but ill informed patients, is one of the most profitable drugs the pharmaceutical industry has ever come up with. Sales account for a quarter of Pfizer's $ 32 billion annual sales. Expected to gross more than $ 10 billion this year, Lipitor is poised to become the largest-selling pharmaceutical in history, surpassing Pfizer's other wonder drug, Viagra.

But the price to society is much higher than a mere 8 to 10 billion dollars. Lipitor and other drugs in the statin class, such as Bayer's version Baycol - removed from the market by its maker - are not only lowering cholesterol. These drugs apparently ruin perfectly good lives with "side effects" that lead to slow degradation into physical disability. The story of Doug Peterson and other residents of Tahoe City may be coldly dismissed as "anecdotal evidence", but there is no excuse for scientific statistical sofistry. Every tragedy is real - when it happens to you, the risk is 100%.

Let's look at the pharmaceutical profit model for a moment. Drugs are developed and they have to be sold, otherwise - no profit. In the case of Lipitor and its similars, that means a market has to be created. Cholesterol, a beneficial substance in the human body, is targetted as a bad sign of impending heart disease. Drugs are promoted to "lower cholesterol". Mind you, not to prevent heart disease but to turn off the blinking warning lights. Billions are made, a huge empire of multinational corporations is built to "take care of our health" - by selling us drugs. National economies are all but bankrupted by the costs of health care, most of it to pay for drugs. What's more, national and personal economies are also bearing the cost - sometimes vastly greater than the mere cost of a prescription - of these drugs' side effects, the cost of drug induced illness and disability.

Who is responsible? The drug barons? The medical researchers? The media which never told us?Or none of them?

I like what Karla, Doug's wife, has to say: "We are hoping he is going to get better. That's our number one goal. Anger is a waste of energy at this point. We are trying to recover and get the word out."

Also Doug is taking the matter with a good deal of philosophy: "At this point, I consider myself lucky I'm not in a wheelchair," says Doug, who is currently in phsyical therapy. "There are no guarantees in life. Your birth certificate doesn't come with a warranty."

In other words: Do it yourself. The responsibility is ours. Help get the word out about what is really happening.

Also see links on the cholesterol scam at the end, and
particularly this one, which pulls the rug from underneath the recommendations to "get your cholesterol down" by all means, even with medication that has serious side effects.

January 29, 2004

LIFE AFTER LIPITOR: Is Pfizer product a quick fix or dangerous drug? Residents experience adverse reactions

(Article originally found in Tahoe Tribune)

By Melissa Siig, Tahoe World Staff

At first glance, Tahoe City resident Doug Peterson looks like he is recovering from a stroke.

His speech is slurred, he has difficulty walking in a straight line, and he can't sign his own name. By afternoon, he is so fatigued he has to sit down for the rest of the day. When asked his age, Peterson says he is 52. His wife Karla, standing nearby, corrects him. He is 53.

Doug has never had a heart attack, and until the onset of the symptoms almost three years ago, was an active skier, biker and scuba diver. Now he is limited to walks on the treadmill. Doug traces his problems to a drug he started taking almost three years before his health began deteriorating - Lipitor. Two other Tahoe City locals have also experienced negative side effects from taking Lipitor or other statins, the name for a family of cholesterol-fighting pills.

While there is no concrete evidence linking Doug's health problems to Lipitor, after doing years of research, meeting with doctors and talking to other statin sufferers all over the world online, he and Karla are convinced of the connection. Pfizer, the maker of Lipitor, claims the drug is effective in lowering cholesterol and has minor side-effects. But as Doug and others would ask, is it worth it?

WONDER DRUG OR DANGEROUS PILL?

Doug, who has hereditary high cholesterol, was first prescribed Mevacor, a statin made by Merck, in 1998. Six months later, his doctor had him switch to Lipitor, which comes in higher doses, and upped his dosage from 10 to 20 mg. His cholesterol dropped from 285 to a low of 160.

"The doctor was very pleased," said Doug, "but meanwhile the symptoms started."

In the fall of 2000, Doug began having restless sleep patterns. His twitching and flying arms got so bad that Karla had to sleep in another room. One time, Doug even fell out of bed. The couple didn't think anything was seriously wrong until a few months later when Doug started slurring his words. This was followed by a loss of balance and the beginning of what Doug calls the "statin shuffle" - a slow, wobbly walk across a room. Next to slide was Doug's fine motor skills. It took him five minutes to write four words, much of which was illegible. Finally, he tired easily and his cognitive memory processing diminished. He had trouble following books with complex plots.

Confounded by Doug's illness, over the next two years the Petersons traveled all over California meeting with neurologists, internists and acupuncturists. Doug had MRIs, brain scans and neurofeedback tests done. Last February, Doug's doctor suggested he go off Lipitor to see if the drug was causing his health problems. After three weeks, the